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Protective piperidone can be used for synthesis and transformation reactions that have attracted much attention, including Knoevenagel reaction, heterogeneous Diels-Alder reaction, and the formation of N-(4-piperidyl) hydroxyindole. The raw material for synthesis of GABA analogues by direct Barbier- type addition reaction of alkyl phosphonate.

N-Benzyloxycarbonyl-4-piperidone

1-benzyloxycarbonyl-piperidin-4-one

1-carbobenzyloxy-4-piperidone

1-Cbz-4-piperidinone

Benzyl 4-oxo-1-piperidinecarboxylate

1-Piperidinecarboxylic acid, 4-oxo-, phenylmethyl ester

1-(Benzyloxycarbonyl)-4-piperidinone

1-Z-4-Piperidone

4-Oxo-1-piperidinecarboxylic Acid Benzyl Ester

1-Cbz-4-piperidone

benzyl 4-oxopiperidine-1-carboxylate

1-Cbz-piperidin-4-one

1-Benzyloxycarbonyl-4-piperidine

N-CBZ-4-piperidone

1-Carbobenzoxy-4-piperidone

4-oxo-piperidine-1-carboxylic acid benzyl ester

MFCD00673144

Chemical Properties 
Colourless Oil

Uses 
Protected piperidinone that can undergo interesting synthetic transformations including the Knoevenagel reaction,1 hetero-Diels-Alder reactions,2 and reactions to form N-(4-piperidinyl)oxindoles.

General Description 
1-Z-4-Piperidone is the starting material in biheteroaromatic diphosphine oxides-catalyzed stereoselective direct aldol condensation reactions.

Product Name	1-(Benzyloxycarbonyl)-4-piperidinone
CAS NO.	19099-93-5
EINECS	606-227-7
Meltling Point	38-41°C
Boiling Point	384.1±42.0 °C at 760 mmHg
Flashing Point	186.1±27.9 °C
Molecular Formula	C13H15NO3
Molecular Weight	233.263
Purity	99%
Density	1.2±0.1 g/cm3
PSA	46.61
LogP	1
Refractive Index	1.56
Vapour  pressure	0.0±0.9 mmHg at 25°C
Appearance	White crystalline powder / White to pale yellow Solid or Lliquid
HS Code	2933399090
Shelf Life:	2years
Storage	Sealed in dry,2-8°C
Stability	stable at room temperature and pressure Materials to Avoid: Oxides
Solubility	Chloroform, Dichloromethane, Ethyl Acetate, Methanol