A 2006 study determined that Δ1-testosterone has a high androgenic and anabolic potency even without being metabolized, so it can be characterized as a typical anabolic steroid. Δ1-Testosterone binds in a manner that is highly selective to the androgen receptor (AR) and has a high potency to stimulate AR-dependent transactivation. In vivo, an equimolar dose of 1-testosterone has the same potency to stimulate the growth of the prostate, the seminal vesicles and the androgen-sensitive levator ani muscle as the reference anabolic steroid testosterone propionate, but unlike it, Δ1-testosterone also increases liver weight.
Doping with Δ1-testosterone can be detected in urine samples using gas chromatography.
A prodrug of Δ1-testosterone is Δ1-androstenedione, which may be synthesized from stanolone acetate.
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