Pemetrexed disodium

Synonyms: n-[4-[2-(2-amino-4,7-dihydro-4-oxo-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid disodium salt;PEMETREXED DISODIUM;PEMETREXED DISODIUM(ALIMTA);PEMETREXED SODIUM;PEMETREXED;2-[4-[2-(4-Amino-2-oxo-3,5,7-triazabicyclo[4.3.0]nona-3,8,10-trien-9-yl)ethyl]benzoyl]aminopentanedioic acid disodium salt;PEMETREXED DISODIUM 99%;PEMETREXED DISODIUM 2.5H2O 

CAS: 150399-23-8 

MF: C20H19N5Na2O6 

MW: 471.37 

Product Categories: Molecular Targeted Antineoplastic;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;LY-231514 

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storage temp.  -20°C Freezer 

Chemical Properties Crystalline Solid 

Usage Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively 

Usage Multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Antineoplastic .