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Pentadecapeptide BPC 157 (2mg/vial)

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Brand: merry@chembj.com
型号: 137525-51-0
规格: 99%
Price: 1.00USD/vial
Min.Order: 10 vial
Supply 10000 vial
Delivery: Shipment within 3 days since the date of payment
Address: China
Valid until: Never Expire
Updated on: 2017-12-13 10:43
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Details
 pentadecapeptide BPC 157
Alias : Booly Protection Compound 15, Pentadecapeptide, BPC 157 
CAS : 137525-51-0 
Sequence : Gly-Glu-Pro-Pro-Pro-Gly- Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val 
MF : C62H98N16O22 
MW : 1419.53552 
Purity : 99% 
Specification : 2mg/vial 
Appearance : White Lyophilized Powder 
Storage : Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. 
Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C. 
Abstract:
Stable gastric pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, M.W. 1419) may be the new drug stable in human gastric juice, effective both in the upper and lower GI tract, and free of side effects. BPC 157, in addition to an antiulcer effect efficient in therapy of inflammatory bowel disease (IBD) (PL 14736) so far only tested in clinical phase II, has a very safe profile, and exhibited a particular wound healing effect. It also has shown to interact with the NO-saystem, providing endothelium protection and angiogenic effect, even in severely impaired conditions (i.e., it stimulated expression of early growth response 1 gene responsible for cytokine and growth factor generation and early extracellular matrix (collagen) formation (but also its repressor nerve growth factor 1- A binding protein-2)), important to counteract severe complications of advanced and poorly controlled IBD. Hopefully, the lessons from animal studies, particularly advanced intestinal anastomosis healing, reversed short bowel syndrome and fistula healing indicate BPC 157s high significance in further IBD therapy. Also, this supportive evidence (i.e., no toxic effect, limit test negative, LD1 not achieved, no side effect in trials) may counteract the problems commonly exercised in the use of peptidergic agents, particularly those used on a long-term basis.

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