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Exemestane Aromasin (albert@kafenbio.com)

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Brand: kafen
型号: 107868-30-4
规格: 99.5%
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Updated on: 2016-09-08 09:32
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1.Quick Details:
 
Product Name Exemestane Aromasin 
Chemical Name Aromasin
CAS Number 107868-30-4
Molecular Formula C20H24O2
Molecular Weight 296.4
Melting Point 191~195°C
Assay 99.5%
Appearance White powder
 
2.Product Description:

Exemestane is a steroidal Aromatase Inhibitor (AI) that is most commonly known as Aromasin. In fact, the Aromasin brand name is the only pharmaceutical grade brand of the Exemestane AI due to the tight patent Upjohn has maintained on the product. While tightly controlled by the pharmaceutical giant, Aromasin is available in numerous countries around the globe.
 
Aromasin was first released on the U.S. market in 2000 after shortly gaining FDA approval a few months prior in 1999. The primary purpose of use as with most AI's would be to combat breast cancer in post-menopausal women. Shortly after, the AI would begin to gain a lot of popularity among anabolic steroid users for its ability to protect against estrogenic related side effects. This action is very similar to the older and more popular AI's in Arimidex and Femara It would also gain a fair amount of popularity in Post Cycle Therapy (PCT) plans among steroid users. It was not the first AI to gain such popularity but would prove to be a little more advantageous for this purpose than most AI's
 
Aromasin is officially classified as a steroidal suicide Aromatase Inhibitor, and carries the ability to inhibit the aromatase enzyme, which is responsible for the production or conversion of testosterone to estrogen. Aromasin has the ability to block aromatization, which in turn inhibits the production of estrogen, and thereby lowers the body's serum estrogen levels. This will prove useful to breast cancer patients as breast cancer often feeds off the estrogen hormone. It will also prove useful to the anabolic steroid user.
 
Many anabolic steroids have the ability to increase estrogen levels due to the aromatase process, specifically the conversion of testosterone to estrogen. This can lead to gynecomastia and water retention. Excess water retention can also promote high blood pressure when it becomes severe. Steroids that do not carry a strong estrogenic nature can also cause these effects, most notably gynecomastia if they carry a progestin nature. A prime example would be Nandrolone, which while it aromatizes only does so at 20% the rate of testosterone. However, it also carries a strong progestin nature, and progesterone has been well noted for carrying the ability to stimulate the estrogenic mechanism in the mammary tissue. By administering Aromasin during the use of anabolic steroids, this will inhibit the aromatase process, lower estrogen levels and protect the individual from estrogenic side effects. How effective is Aromasin? The product claims on average to have the ability to lower serum estrogen levels by 85%.

3.Product Application:

In a therapeutic setting, by blocking the aromatase enzyme, Aromasin actively prohibits the cancer from feeding off the hormone necessary to its survival. It has been proven highly effective for this purpose, but only after the use of the Selective Estrogen Receptor Modulator (SERM) Nolvadex (Tamoxifen Citrate) has failed. While effective, it is also not as commonly used as Arimidex for this purpose as Arimidex largely maintains itself as the primary AI in breast cancer treatment not only among post-menopausal women but in a host of breast cancer scenarios.
 
Then we have Aromasin as an anti-estrogen for the anabolic steroid user. By understanding its functions and traits you should already understand the effects of Aromasin in this regard. Excess estrogen levels can promote gynecomastia and water retention and possibly high blood pressure as a secondary issue. However, keep in mind such effects are not possible with all anabolic steroids, primarily it must carry an estrogenic nature, it must be able to aromatize to lead to such effects or carry a progesterone nature. Testosterone is the primary aromatizing steroid, but testosterone derived steroids like Dianabol can also promote strong estrogenic action. Then we have the Boldenone (Equipoise) hormone, and while it only aromatizes at 50% the rate of testosterone, this is still enough to cause an estrogen buildup in some. Finally, we're left with 19-nortestosterone (19-nor) anabolic steroids. 19-nor compounds will primarily include all forms of Nandrolone and Trenbolone. As discussed Nandrolone aromatizes at 20% the rate of testosterone, but it also carries a very strong progestin nature. This can promote a fair amount of estrogenic activity in many men. As for Trenbolone, it does not aromatize at all, but its moderately strong progestin nature can make gynecomastia a possibility depending on the individual's sensitivity. When use is coupled with an aromatizing steroid, this will greatly enhance the odds of gynecomastia. Regardless of the steroid in question, Aromasin can offer protection from the estrogenic effects.
 
An important note: Aromasin will have no affect on dihydrotestosterone (DHT) derived anabolic steroids as they do not convert to estrogen. Such steroids cannot lead to gynecomastia or excess water retention; it is impossible. The exception would be Anadrol, while a DHT derivative, it carries with it a strong estrogenic nature. However, while estrogenic action is present, the hormone does not aromatize, meaning there is no aromatization for Aromasin to inhibit. The use of an AI will not affect the estrogenicity of Anadrol. For protection from such a steroid, the individual will need to inhibit activation of the estrogenic mechanism, and this will make SERM's the first line of defense.

4.Function:

Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of these hormones.

In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.
 
5.COA:
 
TEST ITEMS SPECIFICATION RESULTS
Description White Crystalline Powder White Powder
Identification Positive Positive
Assay(by HPLC) 98.0~102.0% 99.5%
Absorbance(E1cm) 465~495 482.5
Melting Point 191~195°C 193.5~195.0°C
Loss On Drying 0.5%max 0.19%
Specific Rotation +288°~ +298° +290.2°
Residue On Ignition 0.1%max 0.03%
Related Substances Total:1.5%max <1.3%
  Single:0.5%max <0.4%
Residue Solvents 0.2%max 0.10%
Heavy metals 20PPm max <10PPm
 
 6.Related Products:
 
Testosterone Acetate Trenbolone Acetate MGF
Testosterone Cypionate Trenbolone Enanthate PEG MGF
Testosterone Decanoate Boldenone Acetate CJC-1295
Testosterone Enanthate Boldenone undecylenate CJC-1295 DAC
Testosterone Isocaproate Boldenone Cypionate PT-141
TestosteronePhenylpropionate Boldenone Propionate Melanotan-1
Testosterone Propionate Nandrolone Decanoate Melanotan-2
Testosterone Undecanoate Nandrolone phenylpropionate GHRP-2
Mesterone Nandrolone undecylate GHRP-6
Testosterone Sustanon 250 Nandrolone cypionate  Ipamorelin
Clostebol Acetate Nandrolone propionate Hexarelin
Methylandrostanolone Methyltrienolone Sermorelin
Methenolone Enanthate Drostanolone Propionate Oxytocin
Methenolone Acetate Drostanolone Enanthate TB500
Anadrol Stanolone Fragment 176-191
Anavar Tadalafil Triptorelin
Winstrol Vardenafil Tesamorelin
Clomifene citrate Dianabol Gonadorelin
Toremifene citrate Tamoxifen Citrate DSIP 
Finasteride Dapoxetine hydrochloride Selank

7.Hot Steroids List:
 
Testosterone Acetate Trenbolone Acetate
Testosterone Cypionate Trenbolone Enanthate
Testosterone Decanoate Boldenone Acetate
Testosterone Enanthate Boldenone undecylenate
Testosterone Isocaproate Boldenone Cypionate
TestosteronePhenylpropionate Boldenone Propionate
Testosterone Propionate Nandrolone Decanoate
Testosterone Undecanoate Nandrolone phenylpropionate
Mesterone Nandrolone undecylate
Testosterone Sustanon 250 Nandrolone cypionate 
Clostebol Acetate Nandrolone propionate
Methylandrostanolone Methyltrienolone
Methenolone Enanthate Drostanolone Propionate
Methenolone Acetate Drostanolone Enanthate
Anadrol Stanolone
Anavar Tadalafil
Winstrol Vardenafil
Clomifene citrate Dianabol
Toremifene citrate Tamoxifen Citrate
Finasteride Dapoxetine hydrochloride
More More

8.Semi Finished Steroids Solution:
 
Testosterone Enanthate(Primoteston) 250mg/ml / 300mg/ml 
Testosterone Propionate 100mg/ml
Testosterone Cypionate 250mg/ml / 300mg/ml
Testosterone Sustanon 250 200mg/ml / 250mg/ml
Testosterone Supertest 450  450mg/ml
Nandrolone Decanoate (DECA)  200 / 250 / 300mg/ml
Trenbolone Acetate  100mg/ml
Trenbolone Enanthate(parabola) 200mg/ml 
Drostanolone Propionate (Masteron) 100mg/ml
Boldenone Undecylenate (Equipoise) 200mg/ml / 300mg/ml
Methenolone Acetate (Primobolone) 100mg/ml
Anomass 400mg/ml
Ripex 225mg/ml
Tritren 180mg/ml
More More

9.Related Peptides:
 
Peptides List Specification
MGF 2mg
PEG MGF 2mg
CJC-1295 with DAC 2mg
CJC-1295 without DAC 2mg
PT-141 10mg
MT-1(Melanotan-1) 10mg
MT-2(Melanotan-2) 10mg
GHRP-2 5mg
GHRP-2 10mg
GHRP-6 5mg
GHRP-6 10mg
Ipamorelin 2mg
Hexarelin 2mg
Sermorelin 2mg
Oxytocin 1g/2mg
TB500 2mg
pentadecapeptide BPC 157 2mg
Triptorelin 2mg
Tesamorelin 2mg
Gonadorelin 2mg
Gonadorelin 10mg
DSIP 2mg
Selank 5mg
Epitalon 10mg
AOD-9604 2mg
ACE 031 1mg
GDF-8 1mg(-20ºC)
Thyrotropin TRH 1g
Follistatin 315 1mg(-20ºC)
Follistatin 344 1mg(-20ºC)
Deslorelin 20mg
Adipotide 2mg
Alarelin Acetate 79561-22-1
Angiotensin Acetate 58-49-1
Argpressin Acetate 113-79-1
Aviptadil Acetate 40077-57-4
Bivalirudin Trifluoroacetate 128270-60-0
Deslorelin Acetate 57773-65-6
Desmopressin Acetate 16679-58-6
Eledoisin Acetate 69-25-0
Eptifibatide Acetate 148031-34-9
Felypressin Acetate 56-59-7
GLP-1 (7-37) Acetate 106612-94-6
Taspoglutide 275371-94-3
Glucagon Hydrochloride 16941-32-5
Lixisenatide 320367-13-3
Gonadorelin Acetate 34973-08-5
Leuprorelin Acetate 53714-56-0
Lysipressin Acetate 50-57-7
Nafarelin Acetate 76932-56-4
Octreotide 79517-01-4
Ornipressin Acetate 3397-23-7
Secretin Acetate 108135-74-8
Somatostatin Acetate 38916-34-6
Splenopentin Acetate 105184-37-0
Terlipressin Acetate 14636-12-5
Teriparatide Acetate 52232-67-4
Triptorelin Acetate 57773-63-4
Vasopressin Acetate 9034-50-8
Bate-Amyloid(1-42)human 107761-42-2
Abarelix Acetate 183552-38-7
Endothelin-1 Acetate 117399-94-7
CRF (human, rat) Acetate 86784-80-7
CRF (ovine) Trifluoroacetate 79804-71-0
Dynorphin A (1-13) Acetate 72957-38-1
Enfuvirtide Acetate (T-20) 159519-65-0
Fertirelin Acetate 38234-21-8
GRF (human) Acetate 83930-13-6
Liraglutide 204656-20-2
Dalmarelin Acetate 61012-19-9
Nesiritide Acetate (BNP-32) 114471-18-0
Pramlintide Acetate 196078-30-5
Salmon Calcitonin Acetate 47931-85-1
tesamorelin 106612-94-6
Tetracosactide Acetate (ACTH 1-24) 16960-16-0
Thymosin α1 Acetate 14636-12-5
Thymosin β4 Acetate 77591-33-4
Atosiban Acetate 90779-69-4
Cetrorelix Acetate 130143-01-0
Exenatide Acetate 141732-76-5
Histrelin Acetate 76712-82-8
Taltirelin Acetate 103300-74-9
Vapreotide Acetate 116430-60-5
Gonaderelin 33515-09-2
Cecropin B 80451-05-4
Oxytocin Acetate 50-56-6
Sincalide 25126-32-3
Protirelin 24305-27-9
Ganirelix acetate 123246-29-7

10.SARMs:
Ostarine (MK-2866) CAS: 841205-47-8
Cardarine (GW-501516) CAS: 317318-70-0
Andarine (S4) CAS: 401900-40-1
Ligandrol (LGD-4033) CAS: 1165910-22-4
Ibutamoren (MK-677) CAS: 159752-10-0
RAD140 CAS: 118237-47-0
SR9009 CAS: 1379686-30-2
YK11 CAS: 431579-34-9
More

11.Sex Enhancers:
Avanafil CAS: 330784-47-9
Vardenafil CAS: 224785-91-5
Dapoxetine CAS: 119356-77-3
Tadalafil CAS: 171596-29-5
Vardenafil Hydrochloride CAS: 431579-34-9
Dapoxetine Hydrochloride CAS: 431579-34-9
Yohimbine Hydrochloride CAS: 65-19-0
10.APIs:
T3 CAS: 55-06-1
T4 CAS: 51-48-9
Ethyl Oleate(EO) CAS: 111-62-6
Benzyl Alcohol (BA) CAS: 100-51-6
Benzyl Benzoate (BB) CAS: 120-51-4
Grape Seed Oil (GSO) CAS: 85594-37-2
2,4-Dinitrophenol (DNP) CAS: 51-28-5
1,3-Dimethylpentylamine (DMAA) CAS: 13803-74-2
4-Acetamidophenol (Paracetamol) CAS:103-90-2
Tauroursodeoxycholic Acid (TUDCA) CAS: 14605-22-2
Dextromethorphan Hydrobromide (DXM) CAS: 6700-34-1

12.Company Introduction:

(1) High Quality:Kafen Biotech is a steroids peptides pharmaceuticals manufacturer with its own lab and factory. The purity of  our product is tested by our quality department before it is shipped to  our clients.  Mostly steroids are 99% purity and approved by SGS,CTI and ITS.
(2) Favorable Price: Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.
(3) Safe Fast Delivery: After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried
(4) Available Shipment Way: EMS,HongKong Post,DHL,TNT,UPS,FedEx,Registered Mail,Air Express,Sea Vessel etc
(5) After Sale Service: We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you
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