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CAS:9004-32-4
Molecular formula: R (N) OCH2COONA
Melting point: 300 degrees C
Water soluble: soluble commonly used sodium salt.
The white flocculent powder, odorless, tasteless, non-toxic. Soluble in water, forming a transparent colloidal liquid, neutral solution. Light, thermal stability. Moisture absorption. Insoluble in acid, ethanol, acetone, phenol, chloroform, benzene, insoluble in methanol, ethyl ether. Cellulose derivative carboxymethyl substituents, alkaline cellulose treated cellulose with sodium hydroxide, and chloroacetic acid was prepared. There are 3 hydroxyl groups that can be replaced by the glucose unit of cellulose, so the product with different displacement can be obtained. Average per 1g dry weight guide 1mmol carboxymethyl, in water and dilute acid is not dissolved, but can be used for ion exchange chromatography. Carboxymethyl pKa in pure water is about 4, about 3.5 in NaCl 0.5mol/L, is a weak acid cation exchanger, usually above pH4 for the separation of neutral and alkaline proteins. 40% or more hydroxyl group is a stable high viscosity colloid solution which is soluble in water.
Sodium carboxymethyl cellulose
As white or milky white fibrous powder or granule, no odor, no smell, with moisture absorption. Easy to disperse in water into a colloidal liquid clarity, insoluble in organic solvents such as ethanol.
Sodium carboxymethyl cellulose
Mice by mouth
LD5027g/kg, ADI
Do not make special provisions
(FAO/WHO, 1994).
GRAS (FDA, 182.17452000).
Sodium carboxymethyl cellulose - Methods of use
CMC will be directly mixed with water, mixed into a paste after the glue, backup. In the configuration of CMC paste adhesive, adding a certain amount of clean water in the cylinder with ingredients mixing device, mixing device in the open case, CMC will slowly spread to the ingredients in the cylinder, stirring constantly, make water and CMC fusion, CMC can fully dissolve completely. In the CMC melt, the uniform scattering, and stirring, the purpose is "to prevent CMC and water meet, agglomeration, agglomeration, reduce the dissolved amount of CMC problem, and improve the dissolution rate of CMC. Mixing time and CMC completely dissolved time is not consistent, is the two concepts, in general, the time of mixing than CMC completely dissolved in a much shorter time required, the time required for the two depending on the specific circumstances.
The basis of determining the time required for the complete dissolution of CMC has several aspects:
(1) CMC and water completely bonded, there is no solid liquid separation between the two phenomena;
(2) the mixture of paste is in a state of uniform and uniform, and the surface is smooth and smooth;
(3) the color of mixed paste is close to colorless and transparent, and there is no granular object in paste. From the CMC is put into the mixing tank and water mixture to start, to CMC completely dissolved, the time required for the 20 ~ 10 hours.
Sodium carboxymethyl cellulose
The main indicators to measure the quality of CMC are the degree of substitution (DS) and the purity of the product. The properties of CMC are different in general DS, the degree of substitution increases, the solubility is enhanced, and the transparency and stability of the solution are better. According to reports, the degree of substitution of CMC in 0.7 ~ 1.2 is better transparency, its aqueous solution viscosity at pH value of 6 to 9 when the maximum. In order to ensure its quality, in addition to the selection of etherification agent, but also must consider the impact of some factors to replac degree and purity, such as between alkali and etherifying agent dosage, etherification time, moisture content, temperature, DH value, solution concentration and salts.
Be careful
(1) this product with strong acid and alkali and heavy metal ions (such as aluminum, zinc, mercury, silver, iron, etc.) and is taboo.
(2) the intake of this product is
0 ~ 25mg / kg / d.
An overview of sodium carboxymethyl cellulose
Toxic categories: toxic substances
Toxicity classification: low toxicity
Flammability: Combustible fire, spicy smoke discharge containing sodium
Fire extinguishing agent: water, carbon dioxide, dry powder, sand
Safety terminology
S24/25
Avoid contact with skin and eyes.
Risk term
R40
Limited evidence of a carcinogenic effect.
