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MK-677( Ibutamoren)
Synonyms: Ibutamoren, CHEMBL13817, S1151_Selleck, MK-677
CAS No.: 159752-10-0
Molecular Weight: 624.77
Molecular Formula: C28H40N4O8S2
Purity: 99%
Package: Be packed according to the customer requirements and packaging specifications.
Appearance: White crystalline powder
Storage; Store at -20° C
Specificity: MK-677 selectively binds GH secretagogue receptors in certain tissues.
Purity: >99% (HPLC analyzed).
Stability: Store at at 20 °C in dry place until the expiration date.
Source: Chemical Synthesis
Half-life: 24 hours
Description:
Ibutamoren (developmental code names MK-677, MK-0677, L-163,191) is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a G-H secretagogue,mimicking the G-H-stimulating action of the endogenous hormone ghrelin.It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including G-H and insulin-like IGF-1, but without affecting cortisol levels.It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with G-H deficiency,and human studies have shown it to increase both muscle mass and bone mineral density,making it a promising therapy for the treatment of frailty in the elderly.It also alters metabolism of body fat and so may have application in the treatment of obesity.
