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Hydrocortisone Acetate
Purity: 99% ;
CAS Registry Number: 50-03-3 ;
Grade: Pharmaceutical Grade ;
MF: C23H32O6 ;
MW: 404.5 ;
EINECS: 200-004-4 ;
Purity: 99% ;
Appearance: White or white-off crystalline powder ;
Melting point: 223 º C ;
Density: 1.26 g/cm3 ;
Boiling Point: 576.6 oC at 760 mmHg ;
Flash Point: 196.2 º C ;
Storage Temperature: 0-6° C ;
Refractive index: 1.572 ;
Solubility: Insoluble (slightly soluble in alcohol and in chloroform) ;
Product Implementation Quality Standard: USP, EP .
Description:
Hydrocortisone acetate is an adrenal hormone drugs, white crystalline powder, odorless, bitter taste. The melting point is 216 ~ 222 ℃, right optical. Slightly soluble in ethanol, ether, chloroform, acetone, insoluble in water. It was synthesized by In 17α- hydroxy progesterone.
Hydrocortisone acetate has important physiological activities such as anti-inflammatory, anti-viral, anti-allergic, anti-shock, reducing inflammatory exudation effect, commonly used in clinical adrenal insufficiency and autoimmune diseases. Preparations are injection, tablets, ointments and eye drops. Adding a small amount of hydrocortisone acetate in some cosmetics cortisol can increase the efficacy of anti-allergy and improve the degree of whitening of the skin, but long-term using of such substances can cause the skin produce hormone-dependent disease. Our cosmetics cosmetics specifications prescribedthathormone substances can not be added..
This medication is used to treat hemorrhoids and itching/swelling in the rectum and anus. It is also used with other medications to treat certain intestinal problems (such as ulcerative colitis of the rectum and other rectal/anal inflammatory conditions).Hydrocortisone suppositories help to relieve rectal pain, itching, bloody diarrhea, and bleeding by reducing swelling (inflammation) directly in the rectum and anus. Hydrocortisone belongs to a class of drugs called corticosteroids.
Medical Uses
hydrocortisone acetate injection is used to treat the following:
Infection caused by the Trichinae Parasite; Sarcoidosis; Diagnostic Test For Cushing's Syndrome; Disease with Enlarged Lymph Tissue, Spleen and Liver, Chronic Malignant T-Cell Lymphoma of the Skin, Non-Hodgkin's Lymphoma, Type of Leukemia - Acute Lymphocytic Leukemia, Increased Calcium in the Blood from Cancer, Thyroid Gland Inflammation, Condition caused by Excess Secretion of Male Hormones, Addison's Disease, Severely Decreased Function of the Cortex of Adrenal Gland, Decreased Function of the Adrenal Gland, Inflammation of the Joints due to Gout, Disease in which Body has Immune Response Against Itself, Destruction of Red Blood Cells by Body's Own Antibodies, Constitutional Aplastic Anemia.
hydrocortisone acetate injection may also be used to treat:
Severe Newborn Breathing Problem with Blue Discoloration, Shock caused by a Severe Bacterial Infection
Technical Test Sheet
|
Items of analysis |
Specification |
Results |
|
Characters |
Withe to yellowish-withe crystalline powder |
Almost withe crystalline powder |
|
Melting point |
34-39 |
36 |
|
Loss on drying |
≤0.50% |
0.31% |
|
Optical rotation |
+7°~+11° |
7.5° |
|
Assay |
97%~103% |
99.08% |
|
Conclusion |
Conforms the Enterprise Standard |
|
