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Pharmaceutical Raw Materials Respiratory System Drugs Roflumilast for COPD 162401-32-3

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Updated on: 2017-06-17 16:35
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 Pharmaceutical Raw Materials Respiratory System Drugs Roflumilast for COPD 162401-32-3
Basic Info.
Roflumilast
Synonyms: ROFLUMILAST;3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide;B 9302-107;BY 217;BYK 20869;Daxas;Roflumilast / 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide;3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide 
CAS: 162401-32-3 
MF: C17H14Cl2F2N2O3 
MW: 403.21 
MP: 158°C 
storage temp.  Refrigerator 
Chemical Properties Crystallin Solid 
Usage Selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease 
Purity: 99%
Usage: API
Package: 1KG foil bag; 25Kg drum
Description:
Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibition of the PDE4 isoenzyme in lung cells, roflumilast is indicated for the management of chronic obstrtuctive pulmonary disease (COPD) exacerbations. Treatment with Roflumilast is associated with an increase in psychiatric adverse reactions, including suicide and suicidal attempts.
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