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| Product Name | MK-677 |
| Other Name | Ibutamoren |
| Purity | 98%min by HPLC |
| CAS No. | 159752-10-0 |
| M.W. | 624.776 |
| M.F. | C27H36N4O5S |
| Melting Point | 170-172ºC |
| Appearance | Off-yellow fine powder |
Description:
Ibutamoren (MK-677,L-163,191)acts as a potent,orally active growth hormone secretagogue,mimicking the GH stimulating action of the endogenous hormone ghrelin.It has been demonstrated to increase the release of,and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1,but without affecting cortisol levels.It is currently under development as a potential treatment for reduced levels of these hormones,such as in growth hormone deficient children or elderly adults,and human studies have shown it to increase both muscle mass and bone mineral density,making it a promising therapy for the treatment of frailty in the elderly.It also alters metabolism of body fat and so may have application in the treatment of obesity.
Application
An experimental drug meant to control lipids and increase the level of HDL,or good cholesterol,in the bloodstream.A cell-permeable,thiazolyl compound that acts as a potent,high affinity,PPARd agonist.
Usage
An experimental drug meant to control lipids and increase the level of HDL,or good cholesterol,in the bloodstream.A cell-permeable,thiazolyl compound that acts as a potent,high affinity,PPARδ agonist.Exhibits selectivity for PPARδ compared to PPARα and PPARγ.Does not exibit any activity against other nuclear or non-nuclear receptors.Reported to increase cholesterol efflux and ABAC1 expression in macrophages,fibroblasts,and intestinal cells.
COA
| Product Name | MK-677 mesylate | CAS NO. | 159752-10-0 | |
| Batch No | BDL160410 | Quantity | 800grams | |
| Manufacturing date | 2016..04.10 | Molecular formula | C27H36N4O5S.CH4O3S | |
| Test date | 2016.04.11 | Molecular weight | 624.776 | |
| Test based on enterprise standard | ||||
| Teat item | Component | Specification | Result | |
| Appearance | Light yellow powders | Pass | Pass | |
| 1HNMR | Confirms to structure | Pass | Pass | |
| Assay(HPLC) | Purity | ≥98.0% | 99.2% | |
| LC-MS | Confirms to MW | Pass | Pass | |
| Specific Rotation | [a]25 365 | -15.71 | -15.9 | |
| Storage:Preserve in well closed container,store in a cool and dry place,and keep away from strong light and heat. Conclusion:The material complies with in-house standard. |
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