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Product Name: Ursodeoxycholic acid
Synonyms: 3,7-Dihydroxycholan-24-oic acid; 3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid; Ursodiol; 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol; (3alpha,5beta,7alpha)-3,7-dihydroxycholan-24-oic acid;
CAS: 128-13-2
EINECS: 204-879-3
Assay: 99%
Appearance: white powder
Chemical properties: soluble in ethanol, insoluble in chloroform; soluble in glacial acetic acid, dissolved in sodium hydroxide solution.
Category: pharmaceutical raw materials
Extension products: Ursodeoxycholic Acid Capules, Ursodeoxycholic Acid Tablets
Use: increases bile acid secretion, and the changes of bile components, reduce cholesterol in bile and cholesterol, is conducive to the gradual dissolution of cholesterol gallstones, used for surgical treatment of cholesterol stones, stones but can not dissolve bile pigment stones and mixed stones and roentgenopaque. Cholecystitis. Biliary tract inflammation and dyspepsia are also effective.
Ursodeoxycholic acid description:
Ursodeoxycholic acid, also known as ursodiol (USAN) and the abbreviation UDCA, from the root-word for bear urso, as bear bile contains the substance, is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria.
The current uses is as follows:
1. Reduction in gallstone formation, either in patients with gallstones unfit for cholecystectomy, or obese patients undergoing rapid weight loss to prevent gallstone formation.
2. For the treatment of primary biliary cholangitis (PBC).
3. To aim to improve bile flow in patients with cystic fibrosis controversial.
4. In newborn infants with impaired bile flow.
5. After bariatric surgery, to prevent cholelithiasis due to the rapid weight loss with biliary cholesterol oversaturation and also biliary diskinesia secondary to abnormalities in cholecystokinin and biliary enervation.
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