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Finasteride

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Brand: TJ
CAS: 98319-26-7
Assay: 99%
Appearance: White Crystalline Powder.
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Updated on: 2018-11-19 16:58
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Finasteride
CAS No.: 98319-26-7
Synonyms: Finastid; Propecia; Proscar; Finasteride; Finpecia; Prostide; Chibro-Proscar; Finasteridum;
Formula: C23H36N2O2
Exact Mass: 372.27800
Molecular Weight: 372.54400
PSA: 58.20000
LogP: 4.53420
Appearance : white to off-white crystalline powder
Density: 1.065 g/cm3
Melting Point: 253ºC
Boiling Point: 576.6ºC at 760 mmHg
Flash Point: 177.4ºC
Refractive Index: 1.524
Water Solubility: insoluble


Description:

Finasteride: Proscar; Prostide; Raw Powder; Baldness Treatment; Treat Hair Loss; Pharmaceutical Raw Materials


Finasteride is a popular anti-androgen medication manufactured by Merck most commonly known as either Proscar or Propecia. based on the progesterone skeleton, Finasteride belongs to a class of medications known as 5alpha-reductase inhibitors and as such is used for the treatment revolving around type 2 5-AR based occurrences.


This is important for performance enhancers as DHT based anabolic steroids have specific side-effects that may occur that can largely be remedied with the use of a 5-AR inhibitor such as Finasteride.

As a type 2 5-AR inhibitor Finasteride was designed for the purpose of treating hair-loss, prostate enlargement, as well as prostate cancer.


Finasteride is very common among those who supplement with anabolic steroids yet fear hair-loss but there are important things you need to understand before you consider Finasteride use. As an androgen suppressor Finasteride can seriously inhibit the gains made while on cycle, severely and on that basis it is not highly recommended for on-cycle hair preservation.


Propecia (finasteride) is used to treat male pattern baldness (androgenic alopecia) in men. Topically (on the scalp itself) it is of some effect in minimizing further hair loss. In combination with Nizoral and spironolactone (which smells awful, by the way) it can actually reverse loss moderately.


Used for the treatment of prostate disease first. Clinical studies suggest that, with finasteride 1 mg/day, continuous oral 3 months or slightly long can have hair growth, after continuous treatment 1 year hair growth rate to 48%, and can continue to fall off, taking the hair organization 2 years hair growth rate reached 66% ~ 83%.


Specification:

Test Items Specification Test Results
Description White or off-white crystalline powder Off-white crystalline powder
Specific rotation -56°~-60° -58.2°
Identification IR Matches with working standard Complies
HPLC
Solubility Freely soluble in chloroform and in alcohol; Very slightly soluble in water Conform
Heavy metals ≤10ppm <10ppm
Water ≤0.3% 0.22%
Residue on ignition ≤0.1% 0.05%
Relative material Maximum impurities≤0.5% 0.36%
Total impurities≤1.0% 0.52%
Assay 98.5~101.0% 99.68%


Finasteride works by blocking the conversion of the hormone testosterone to dihydrotestosterone in the prostate. It does this by blocking an enzyme called 5-alpha reductase. Dihydrotestosterone is partly responsible for making the prostate enlarge.


Therefore a reduced amount of dihydrotestosterone in the prostate causes it to shrink. This helps you to pass urine more easily.


Physicians use finasteride for the treatment of benign prostatic hyperplasia (BPH), informally known as an enlarged prostate. The FDA-approved dose is 5 mg once a day. Six months or more of treatment with finasteride may be required to determine the therapeutic results of treatment.


If the drug is discontinued, any therapeutic benefits reverse within about 6–8 months. Finasteride may improve the symptoms associated with BPH such as difficulty urinating, getting up during the night to urinate, hesitation at the start of urination, and decreased urinary flow.



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