Product name:Exemestane
Alias:Aromasin;Exemestan;Exemestane
Product Category:Pharmaceutical raw materials and intermediates
Assay:98%min
CAS Registry Number:107868-30-4
Molecular formula:C20H24O2
Molecular Weight:296.40
Appearance:White or Almost White Crystalline Powder
Grade:Pharmaceutical Grade
Certification:ISO9001,GMP,USP,BP
Packaging Details:1-2 kg/aluminum foil bag, 25kg/drum, as required
Usage:Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds
Storage:Shading, confined preservation
Minimum Order Quantity:10g
Production Capacity:10000kg/month
Product Description:
1.Aromasin is a steroidal Aromatase Inhibitor (AI) that is most commonly known as Aromasin.
Aromasin is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.
2.The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.
3.Aromasin lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.
Specifications:
TEST ITEMS SPECIFICATION RESULTS
Description White Crystalline Powder White Powder
Identification Positive Positive
Residue Solvents 0.2%max 0.10%
Absorbance(E1cm) 465~495 482.5
Heavy metals 20PPm max <10PPm
Loss On Drying 0.5%max 0.19%
Specific Rotation +288°~ +298° +290.2°
Related Substances Total:1.5%max <1.3%
Single:0.5%max <0.4%
Melting Point 191~195°C 193.5~195.0°C
Residue On Ignition 0.1%max 0.03%
Assay(by HPLC) 98.0~102.0% 98.64%
Applications:
1.Aromasin was first released on the U.S. market in 2000 after shortly gaining FDA approval a few months prior in 1999. The primary purpose of use as with most AI's would be to combat breast cancer in post-menopausal women. Shortly after, the AI would begin to gain a lot of popularity among anabolic steroid users for its ability to protect against estrogenic related side effects. This action is very similar to the older and more popular AI's in Arimidex and Femara It would also gain a fair amount of popularity in Post Cycle Therapy (PCT) plans among steroid users. It was not the first AI to gain such popularity but would prove to be a little more advantageous for this purpose than most AI's
Aromasin is officially classified as a steroidal suicide Aromatase Inhibitor, and carries the ability to inhibit the aromatase enzyme, which is responsible for the production or conversion of testosterone to estrogen. Aromasin has the ability to block aromatization, which in turn inhibits the production of estrogen, and thereby lowers the body's serum estrogen levels. This will prove useful to breast cancer patients as breast cancer often feeds off the estrogen hormone. It will also prove useful to the anabolic steroid user.
2.Many anabolic steroids have the ability to increase estrogen levels due to the aromatase process, specifically the conversion of testosterone to estrogen. This can lead to gynecomastia and water retention. Excess water retention can also promote high blood pressure when it becomes severe. Steroids that do not carry a strong estrogenic nature can also cause these effects, most notably gynecomastia if they carry a progestin nature. A prime example would be Nandrolone, which while it aromatizes only does so at 20% the rate of testosterone. However, it also carries a strong progestin nature, and progesterone has been well noted for carrying the ability to stimulate the estrogenic mechanism in the mammary tissue. By administering Aromasin during the use of anabolic steroids, this will inhibit the aromatase process, lower estrogen levels and protect the individual from estrogenic side effects. How effective is Aromasin? The product claims on average to have the ability to lower serum estrogen levels by 85%.
Five advantages of making finished steroids by yourself:
1. The cost is only 40-60% of the normal cost
2. They take only a short time to prepare
3. They are easier and cheaper to ship than AMPS or vials
4. Less chance of your order getting seized by customs
5. Unlike vials and AMPS, they come with a refund/reship policy
More details pls contact: Skype: +8618064039730, E-mail: Frank@carnosschem.com