PharmaLegacy Laboratories (Shanghai) Co., Ltd was founded in 10 years ago, After a period of rapid development, it has developed into a co
nsiderable size and effectiveness company of
AutoimmuneDiseasesModelx2a3868enandOsteoporosis Model, NOw it is benchmark companies in 商务服务,医疗服务,医疗保健 industry.
Innovation is the cornersto
nes of PharmaLegacy Laboratories (Shanghai) Co., Ltds success. In the future, PharmaLegacy also hope to co
ntinue to innovate, for the majority of customers to provide Respiratory Disease Modelservice. Over the years, PharmaLegacy always believe that o
nly adhere to innovation and professional, in order to better meet customer demand for Liver Fibrosis Model the main features. details:Carbon tetrachloride (CCl4)-induced hepatic fibrosis and cirrhosis in rodents is a well-established and widely accepted experimental model for the study of liver fibrosis and cirrhosis. In many aspects it mirrors the pattern of human disease associated with toxic damage. For example, the α-SMA ex
pression, Stellate cell activation and key matrix compo
nents including collagen-1, MMPs and their inhibitors TIMPs have been indicated in the pathogenesis of this model. CCl4 induction elicits a reproducible and predictable fibrotic respo
nse in liver, making it a valuable basis for preclinical pharmacology studies of anti-fibrotic and anti-cirrhotic therapeutics and the pathophysiology study of liver fibrosis-cirrhosis-HCC changes
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