Fulvestrant and its intermediate

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Fulvestrant                                                          CAS: 129453-61-8

4,4,5,5,5-Pentafluoro-1-pentanol                                         CAS: 148043-73-6

1-BROMO-9-[(4,4,5,5,5-PENTAFLUOROPENTYL)THIO]-NONANE          CAS: 148757-89-5

17b-Acetyloxy-estra-4,6-diene-3-one                                      CAS: 2590-41-2

Route 1:

7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-

1,3,5(10)-triene-3,17-diol 17-acetate (N-2)                                  CAS: 875573-69-6

Route 2:

(7a,17b)-7-(9-Bromononyl)estra-1,3,5(10)-triene-3,17-diol (N-2)                CAS: 875573-67-4

(7a,17b)-7-(9-Bromononyl)-estra-1,3,5(10)-triene-3,17-diol 17-acetate (N-3)       CAS: 875573-66-3

Route 3:

Estr-4-en-3-one, 17-(acetyloxy)-7-[9-[(4,4,5,5,5-pentafluoropentyl)thio]nonyl]-,(7α+β,17β)- 

Estr-4-en-3-one, 17-(acetyloxy)-7-[9-[(4,4,5,5,5-pentafluoropentyl)thio]nonyl]-,(7α,17β)- 

               

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