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Chinese alias: Olistar; Olistar;
English Name: [(2S) -1-[(2S, 3S) -3-hexyl-4-oxooxetan-2-yl] tridecan-2-yl] (2S) -2-formamido-4-methylpentanoate
English aliases: Xenical; Orlipastat; Orlipastatum; Alli; orlistat;
CAS No. 96829-58-2
Molecular formula: C29H53NO5
Molecular weight: 495.73500
Accurate quality: 495.39200
PSA: 81.70000
LogP: 7.90870
Physicochemical properties
Density: 0.976 g/cm 3
Melting point: <50 C
Boiling point: 615.9 C at 760 mmHg
Flash point: 326.3 unitary C
Refractive index: 1.469
Storage conditions: 2-8 unitary C
The new Jianfei lipid-lowering drug Olix is currently internationally recognized as a new type of Jianfei lipid-lowering drug. The product name on the market is Senico. It was first marketed in New Zealand in 1998. When the annual sales reached US$146 million, it sold US$538 million in 2007. At present, Olixote occupies 80% of the global Jianfei market share, and the annual sales in Hong Kong, China alone, reached 8000. Ten thousand dollars.
Orlistat is a long-acting and effective specific gastrointestinal lipase inhibitor. It is white or white powder at room temperature, insoluble in water and soluble in ethylene chun. It inactivates the enzyme by forming covalent bonds with the active serine sites of gastric lipase and pancreatic lipase in the stomach and small intestinal cavity. Fat in food can not be decomposed into free fatty acids and monoglycerides, so fat can not be absorbed and utilized, thus reducing the body's calorie intake and controlling body weight. The drug does not need to be absorbed throughout the body. The absorption of fat can be inhibited by 30% at commonly used doses. After oral administration, it is rarely absorbed and can be metabolically inactivated in the intestinal tract. The metabolic site is in the gastrointestinal wall. The elimination half-life is about 14-19 hours. about 97% of the products were excreted with feces, of which 83% were excreted in the original form. It can be used clinically in obesity and hyperlipidemia. Generally speaking, 120 mg can be taken orally three times a day during meals or one hour after meals. Weight loss can begin after 2 weeks. It can be taken continuously for 6 to 12 months. If the dose is increased to more than 400 mg per day, its effect will not be enhanced.
Purpose:
The combination of a low calorie diet is suitable for long-term Zhiliao in obese and overweight people, including those who already have obesity-related risk factors. It has the effect of long-term weight control (weight loss, weight maintenance and rebound prevention). Senecio can reduce the risk factors associated with obesity and the incidence of other obesity-related diseases, including hypercholesterolemia and type 2 diabetes.
Orlistat is an obese Zhiliao drug that does not act on the central nervous system. It only acts on the gastrointestinal tract. By inhibiting the lipase in the gastrointestinal tract, it prevents the hydrolysis of triglyceride to free fatty acid and monoglyceride, reduces the absorption of dietary fat (triglyceride) by intestinal mucosa, and promotes the elimination of fat in vitro. Lipase is an essential enzyme for digestion of fat in the gastrointestinal tract. This product can bind to serine residues of gastric and pancreatic lipases, inactivate lipase, prevent it from decomposing fat into free fatty acids, inhibit the utilization and absorption of fat. In addition, this product can also reduce the risk factors associated with obesity. Obesity and overweight people who have moderate dietary control and exercise include long-term Zhiliao in patients with obesity-related risk factors (diabetes, hypertension, dyslipidemia, etc.).
Shenzhen Hualai Biological Technology Co., Ltd. is a high-quality spot company with direct sales from manufacturers. It can inquire for orders and return the full cost of samples.
To produce high-quality products with high standards and efficiency is the consistent purpose of the Wallace people.
Win-win with customers is our development goal. Shenzhen Hualai, the most reliable partner for you
Now the company opens the Internet sales channels, and makes unremitting efforts to serve customers faster and better. The company's products with high purity, stable long-term spot supply, and provide small packaging (Olistar) samples, welcome customers to inspect!
(1) How to ensure the quality of products?
1. Our company is a customer-oriented, integrity-based enterprise, our products are in line with national standards and industry standards. If you are not confident, we can provide samples for your trial. The bulk goods are accepted according to the quality of samples and the implementation standards of products. All the goods can provide inspection reports.
2. It is necessary to sign a formal procurement contract. The quality and after-sale contents of products can be standardized in the contract. once signed, it has legal effect.
3. For mass customized products, the company provides sample testing, and after customer approval, both sides retain samples to carry out production and acceptance testing based on the sample.
(2) Description of purchase process and price of (Olistar)
1. Provide the purchaser's company qualification (business license picture) and sign the purchase contract.
2. The payment method of our company is cash on delivery. Payment is made before 16:00 a day, delivery can be made on the same day, payment can be made after 16:00, delivery can be arranged on the next day, and holidays can be postponed. Delivery within 25 kg by express delivery, more than 25 kg by logistics delivery. The main express delivery companies are: Zhongtong Express, Shunfeng Express, Debang Logistics, etc.
3. Exchange and Return Policy
1) After the arrival of the goods, the buyer should carefully confirm that the goods are in good condition before signing for acceptance, and accept them according to the implementation standards of the products. If the product indicators do not match, we will return the goods.
2) We will carefully pack the goods before delivery, but the process of loading and unloading may lead to scratch and depression of the outer package. If there is no product leakage, it is normal.
3) If there is any leak, please take a photo and deposit the certificate and contact us immediately. We will cooperate to solve the problem.
4) For scientific research and export only
Olistar High purity powder spot supply
Olistar High purity powder spot supply
Olistar High purity powder spot supply
