Diosmin

Although oranges, lemons, and other citrus fruit are known to be an excellent source of vitamin C, these fruit also contain diosmin, a little-known flavonoid compound found to possess antioxidant and anti-inflammatory properties.
First used therapeutically in the 1960s, diosmin is widely available in dietary supplement form. In many cases, diosmin is taken in combination with hesperidin, another citrus fruit flavonoid. A supplement known as "micronized purified flavonoid fraction", or MPFF, is a combination of diosmin with hesperidin, typically in a 9:1 ratio. Diosmin can also be produced by extracting hesperidin from citrus and modifying its components.