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Chinese alias: N-2-pyrimidinyl-4-aminobenzenesulfonamide silver salt; Shangshangning;
English Name: silver (1+) sulfadiazinate
English aliases: silver sulfadiazine; Sulfadiazine silver salt; silver, (4-aminophenyl) sulfonyl-pyrimidin-2-ylazanide; Silver (I) sulfadiazine; Sulfanilsaeure-pyrimidin-2-ylamid, Silber (I) -Salz;
Flamazine; Sulfadiazine Silver; Dermazin; Silver Sulfadiazine; Silver (I) Sulfadiazine; Thermazene; 4-amino-N-pyrimidin-2-yl-benzenesulfonamide; silver sulfadiazinate; Flammazine; sulfanilic acid pyrimidin-2-ylamide, silver (I) -salt; SULFADIAZINE LVER; Silvadene; Silphazine; Silver (I) Sulfadiazine; Silver (I) Sulfadiazine, silver sulfadiazine;
CAS No. 22199-08-2
Molecular formula: C10H9AgN4O2S
Molecular weight: 357.13700
Accurate quality: 355.95000
PSA: 94.32000
LogP: 3.11490
Physicochemical properties
Appearance and properties: solids
Density: 1.496g/cm 3
Melting point: 285 degrees C (dec.) (lit.)
Boiling point: 512.6 C at 760 mmHg
Flash point: 263.8 C
Stability: Stable. Incompatible with strong oxidizing agents.
Steam pressure: 1.28E-10mmHg at 25 degree C
Introduction:
Silver sulfadiazine (INN: Silver sulfadiazine, or silvadene) is a sulfonamide/silver salt antibacterial agent used in the treatment of burn ointment. Studies have found that silver sulfadiazine may increase treatment time -- if used, wounds may take longer to heal, so the authors of the Cochrane Systematic Review do not recommend it. Silver sulfadiazine is usually made into a 1% ointment or water suspension. Brands include Silvadene, Silverex, Silverol, Silvazine, Flamazine, Thermazene, BurnHeal and SSD. These compounds are listed in the WHO Essential Medicines Standard List, which contains the most important drugs required by the Essential Medical and Health System.
Effect:
For the treatment of burn and scald wound infection, besides controlling infection, it can also promote wound dryness, scab formation and healing. After applying the medicine, it turns dark brown when exposed to light. It has the antimicrobial effect of sulfadiazine and the convergence effect of silver salt, and has a strong inhibitory effect on Pseudomonas aeruginosa, which is stronger than metsulfuron.
Indications for silver sulfadiazine:
Silver sulfadiazine is locally used to prevent and treat secondary wound infections after second and third degree burns. It is used to prevent and control the infection of Pseudomonas aeruginosa and Escherichia coli on the wound surface. It also has local convergence effect to promote the drying and scab healing of the wound surface.
silver (1+) sulfadiazinate High purity powder
silver (1+) sulfadiazinate High purity powder
silver (1+) sulfadiazinate High purity powder
