Microwave Sterilization & Drying Equipment

The application of Microwave Sterilization & Drying Equipment in the pharmaceutical industry

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Large amount of facts could indicate that use microwave drying and steriliation of drugs is much better than traditional high temperature sterilization process. This paper will take pills ,oral liquid ,glue capsule, troche for example to expounds the advantage of  the microwave drying and sterilization  in pharmaceutical production line.

A: Oral Liquid Sterilization

In recent years the market comes a new nutritional health products-oral liquid. As is known to all,  oral liquid contain sugar, biological agents and rich nutrition, So it was very easy to pollution. Some of the oral liquid on the market, with no good sterilization, bacteria breeding and producing gas in stores, the accident of poisoning and bottle explosion happen when the users have oral liquid. Some oral liquid production factory, in order to prevent bacterial breed, add preservatives in oral liquid, the results seriously affected the quality of the oral liquid. Using microwave sterilization method, can effectively solve the above problem, below oral liquid use microwave sterilization method for analysis

1) sterilization effect

Traditional methods is use high temperature steam to sterilize, only the oral liquid need to heating to 120 ℃ and keep more than 20 minutes keep ,it can kill bacteria. But microwave sterilization:

A. escherichia coli and bacillus subtilis in microwave field as long as heating to 70 ℃, keep 2 minutes can be all killed.

B. thermophilic bacillus subtilis, fat bacteria, and by traditional method should be heating to 100 ℃, keep 30 minutes, cannot be killed. In the microwave field, the temperature of 70 ℃, and keep the 2 minutes, which were killed. The user feedback information shows that, with 5 kw of microwave sterilization equipment, it takes 50 seconds to kill bacteria, and it takes 35 seconds to kill bacteria with 8 kw microwave equipment.

2) The influence of effective ingredients of oral liquid

According to foreign reports in the literature, use microwave sterilization, drug effective ingredients not decompose. using the traditional method sterilization, drug effective ingredients decomposition is obvious. a pharmaceutical plant in Qinhuangdao do a few samples contrast test t, the results were the same as reports in the literature.

3) microwave processing oral liquid comprehensive economic effect analysis

Oral liquid microwave equipment manufacturer home sterilizing treatment, not only can progress of the product grade, overcome oral liquid the quality of the topic,but also can save a lot of manpower and material resources.

A. Relative to traditional sterilization process, microwave sterilization equipment is lower cost, cover an area of an area small. the traditional high temperature and high pressure equipment, need equipped with boiler pressure cooker, and high cost, covering an area of large.

B. Microwave equipment less energy consumption, high temperature and high pressure equipment more energy consumption.

C. Control staff of microwave equipment is less, only 2-3 people, and high temperature high pressure equipment to be equipped with more than 10 employees to manipulate and control.

D. Microwave equipment noise is small, and high temperature high pressure equipment have noise pollution is serious influence around the environment.

E. Microwave processing oral liquid, belongs to the low temperature sterilization, can keep the original nutrients, the brilliance is clear, taste good; While the high temperature high pressure treatment oral liquid, damaged the nutrients, the brilliance is cloudy, precipitation, poor taste.

To sum up, the microwave sterilization process in oral liquid the application of traditional medicine of the process is to a challenge, is a revolution of the medical technology that can be expected in the near future, all the oral liquid manufacturers are will use the microwave sterilization process oral liquid.

2: Microwave for pills, tablets, capsules of dry and antiseptic processing

The traditional pills, tablets, capsules of dry all use steam sterilization and the tunnel drying oven, which not only need a large number of the production workshop, and even equipped with expensive air conditioning equipment, consume large amounts of energy, and the drying time is very long, generally takes a few hours or a few days. Using microwave equipment on pills, tablets, capsules drying and sterilization, can reduce labor intensity, progress quality, and can ensure that the product's one to sex.

In the pharmaceutical production, in order to ensure that the drugs uniformity and good activities *, often be with the method of raw materials must be made from grain (pills, capsule, tablet). Use the microwave heating and non-thermal effect, dry at low temperature and antiseptic processing, microwave energy direct radiation to drugs, make drug interior temperature, stress, accelerate the transfer of water molecules bound, processed items of water evaporation gradually to the outside, this time in the microwave equipment again with the appropriate hot air, will come out of water evaporation away. In order to ensure the quality of products, should be strictly controlled blast temperature, humidity and flow. Use the microwave drying process not only greatly progress drug product quality, and can greatly shorten the drying time and save a lot of energy, and the economic benefit is very obvious.

In addition, microwave can to all sorts of Chinese and western medicines, herbs, dehydration, drying disinfection, sterilization, pesticides, mouldproof processing. Can greatly facilitate producers to drugs and raw material storage and preservation. Can be expected, the microwave the high technology in this field application will dominate.