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1-(Benzyloxycarbonyl)-4-piperidinone CAS 19099-93-5

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Brand: Hoyan
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Updated on: 2023-06-02 10:31
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Details

Protective piperidone can be used for synthesis and transformation reactions that have attracted much attention, including Knoevenagel reaction, heterogeneous Diels-Alder reaction, and the formation of N-(4-piperidyl) hydroxyindole. The raw material for synthesis of GABA analogues by direct Barbier- type addition reaction of alkyl phosphonate.

N-Benzyloxycarbonyl-4-piperidone

1-benzyloxycarbonyl-piperidin-4-one

1-carbobenzyloxy-4-piperidone

1-Cbz-4-piperidinone

Benzyl 4-oxo-1-piperidinecarboxylate

1-Piperidinecarboxylic acid, 4-oxo-, phenylmethyl ester

1-(Benzyloxycarbonyl)-4-piperidinone

1-Z-4-Piperidone

4-Oxo-1-piperidinecarboxylic Acid Benzyl Ester

1-Cbz-4-piperidone

benzyl 4-oxopiperidine-1-carboxylate

1-Cbz-piperidin-4-one

1-Benzyloxycarbonyl-4-piperidine

N-CBZ-4-piperidone

1-Carbobenzoxy-4-piperidone

4-oxo-piperidine-1-carboxylic acid benzyl ester

MFCD00673144



Chemical Properties 
Colourless Oil

Uses 
Protected piperidinone that can undergo interesting synthetic transformations including the Knoevenagel reaction,1 hetero-Diels-Alder reactions,2 and reactions to form N-(4-piperidinyl)oxindoles.

General Description 
1-Z-4-Piperidone is the starting material in biheteroaromatic diphosphine oxides-catalyzed stereoselective direct aldol condensation reactions.


Product Name 1-(Benzyloxycarbonyl)-4-piperidinone
CAS NO. 19099-93-5
EINECS  606-227-7
Meltling Point 38-41°C
Boiling Point 384.1±42.0 °C at 760 mmHg
Flashing Point 186.1±27.9 °C
Molecular Formula C13H15NO3
Molecular Weight 233.263
Purity 99%
Density 1.2±0.1 g/cm3
PSA 46.61
LogP 1
Refractive Index 1.56
Vapour  pressure 0.0±0.9 mmHg at 25°C
Appearance White crystalline powder / White to pale yellow Solid or Lliquid
HS Code 2933399090
Shelf Life:  2years
Storage Sealed in dry,2-8°C
Stability stable at room temperature and pressure
Materials to Avoid: Oxides
Solubility Chloroform, Dichloromethane, Ethyl Acetate, Methanol





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