tricalcium phosphate(medical)

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Updated on: 2013-09-02 09:20
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Chemical Name:tricalcium phosphate;
Synonyms:Tricalcium bis,        molecular weight:310.18
molecular formula:Ca3(PO4)2      density:3.14 g/cm3
M.P:1670℃,                      refractive index:1.626
CAS: 7758-87-4
β-TCP has similar composition with bone & mineral composition,White amorphous powder,odorlessness。Stability in the air,resolve in hot water,soluble in dilute hydrochloric acid and nitric acid,almost insoluble in water, ethanol and acetic acid.Good biological compatibility,they can degrade at different degree in the physiological environment and can be absorbed by the organic tissues.
detailed description:
(β-TCP)has good biodegradability, biocompatibility, and ability to induce bone,after implanted body, degradation calcium and phosphorus can enter the circulatory system in vivo, the formation of new bone, so a large number used bone tissue repair. But its poor toughness, brittle, poor load bearing. Poly-L-lactic acid (PLLA) because of their good biocompatibility and biodegradability advantages, also used in bone tissue repair.
Specification:
Name         Average particle size     purity      color
β-TCP                   0.5-15um                96%      white
main application
Tricalcium phosphate has good biocompatibility, bioactivity and biodegradability, is good for human hard tissue repair and replacement materials in the biomedical engineering field has been closely watched by the people.
A commonly used medical tricalcium phosphate form of a special-β-tricalcium phosphate. Good biocompatibility, bioactivity and biodegradability, is good for human hard tissue repair and replacement materials as artificial bone materials, has been widely used in orthopedics, plastic and cosmetic surgery, dental, rehabilitation due to trauma, cancer, inflammation, bone disease and other bone defects and bone due to fusion. Can be used as a safe food nutrition fortifier added to enhance calcium intake, can also be used for the prevention or treatment of calcium deficiency symptoms. Also serves as an anti-caking agent in foods, PH value regulating agents, buffers, etc.
β-tricalcium phosphate is mainly composed of calcium and phosphorus, whose composition is similar to the inorganic component of bone matrix, good combine with bone. Animal or human cells in the β-tricalcium phosphate material, normal growth, differentiation and reproduction. Through a large number of experimental studies have shown that: β-tricalcium phosphate bone marrow hematopoietic function without adverse reaction, no rejection, no acute toxicity, will not cancerous, no allergies. Therefore, β-tricalcium phosphate is widely used in joints and spinal fusion, limb trauma, oral maxillofacial surgery, cardiovascular surgery, periodontal and filling voids and so on. As people of β-tricalcium phosphate deepening of the research, its application also appeared in the form of diversification, and in clinical medicine reflects better performance.
The degree of hemolysis <5%, when the β-tricalcium phosphate to be implanted in the human body after body fluids can degrade and absorption of calcium and phosphorus to be absorbed into the body fluid circulation system, implanted in the body after a certain time the β-phosphate tricalcium gradually dissolved away, the formation of new bone. β-tricalcium phosphate combined with autologous bone marrow is an ideal method for treatment of bone defects after implantation no significant local tissue inflammation and other reactions, as a carrier of anti-TB drugs and antibiotics, osteomyelitis stuffer to the affected area, the basic repair of bone defects.
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