Vardenafil

CAS No.: 224785-91-5

M.F.: C23H33ClN6O4S

M.W: 525.06

Description: White or almost white crystalline powder

Melting Point: 191.0°C ~193.0°C

Loss of Drying: NMT 1.0%

Heavy metal: NMT 20ppm

TLC: Only one spot

Assay: NLT 99.5%

Details:   

Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.