Ethynyl estradiol

Synonyms:NOVESTROL;NEO-ESTRONE;ETHYNYLESTRADIOL;ETHINYL ESTRADIOL;LYNORAL;17ALPHA-ETHYNYL-DELTA1,3,5(10)-ESTRA-TRIENE-3,17BETA-DIOL;17ALPHA-ETHYNYLESTRADIOL;17ALPHA-ETHINYLESTRADIOL

CAS:57-63-6

EINECS:200-342-2

MF:C20H24O2

MW:296.4

Melting point: 182-183 ° C (lit.) 

Refractive index :-30 ° (C = 0.4, Pyridine) 

Storage conditions :-20 ° C Freezer

Chemical Properties white to creamy white crystalline powder. Melting point 145-146 ℃ (hemihydrate). 182-184 ℃ (anhydrous). Was dissolved in ethanol, propanol, diethyl ether, chloroform, dioxane, vegetable oil and sodium hydroxide solution, insoluble in water. Odorless.

The purpose of this article is estrogen drugs. Effect with diethylstilbestrol, but 20 times stronger effect. Combined with the use of contraceptives, progestins, synergistic inhibition of ovulation, contraceptive efficacy can be enhanced, and reduce side effects such as breakthrough bleeding. In addition, it can be used for menstrual disorders such as amenorrhea, after a few months, menopausal syndrome, and uterine hypoplasia. For the preparation of contraceptive use.
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