Sorafenib Tosylate

cas:475207-59-1

MF: C21H16ClF3N4O3.C7H8SO3

MW: 637.03

Appearance: Off-white crystalline powder.

Melting point: 225 -235

Loss on Drying: 0.5%max.

Total Impurities: 1.0%max.

Purity by HPLC: 99.0%min.

Sorafenib tosylate Usage And Synthesis :

Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively.

Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively

welcome to contact me ,tina luo,ycgc_int at yccreate dot com  SKYPE:tinaluophar