Letrozole CAS : 112809-51-5

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English Name：4,4'-(1H-1,2,4-TRIAZOL-1-YLMETHYLENE) BIS-BENZONITRILE; CGS-20267; FEMARA; LETROZOL; LetrozoleUsp28; Letrozole99%; CGS-20267, Femara; LETRAZOLE; letrozolex; Lelrozol; 1-[BIS(4-CYANOPHENYL)METHYL]-1,2,4-TRIAZOLE; 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile; 4,4'-(1H-1,2,4-Triazole-1-ylmethylene)bisbenzonitrile; 4,4'-[(1H-1,2,4-Triazole-1-yl)methylene]dibenzonitrile

CAS : 112809-51-5

Molecular Formula: C17H11N5 

Molecular Weight: 285.31

Appearance： White or almost white powder

Usage: 

1.Letrozole is a new generation aromatase inhibitor, is a synthetic derivative of benzyl triazole letrozole by inhibiting aromatase, estrogen levels decline, thereby eliminating the stimulating effect of estrogen on tumor growth.

2. treatment of postmenopausal advanced breast cancer (estrogen receptor, progesterone receptor positive or unknown receptor status), used for anti-estrogen therapy after failure of second-line treatment; 

3.line for locally advanced or spread of postmenopausal breast cancer; 

 for the received standard adjuvant tamoxifen therapy for five years after the extension of the adjuvant treatment of postmenopausal breast cancer patients; 

4 adjuvant therapy for hormone-positive early breast cancer patients.