Thin layer chromatography silica gel preparative plate is formed through the way of the high performance thin layer chromatography silica gel (powder) mixed with a certain quantity of binder or fluorescent indicator. Thickness of thin-layer is about 0.5-2.0mm. This product can be directly used for the separation and purification of active ingredient from pharmaceuticals, pesticide, Chinese herb medicine, organic chemical articles as well as grains and foodstuff substituting for silica gel column chromatography.