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Quick Detail:
Gamma butyrolactone
Alias: GBL;
CAS No.: 96-48-0
EINECS No.: 202-509-5
M. F.: C4H6O2
M. W.: 86.09
Purity: 98.0%
Appearance: Colorless transparent liquid
Description:
Gamma butyrolactone (GBL) is a chemical compound that can be synthesized in laboratories but can also be found in unadulterated wines. On its own, gamma butyrolactone does not have any effects. Nevertheless, when it is absorbed into the blood, it is subjected to the action of lactonase enzymes. These enzymes catalyze the conversion of gamma butyrolactone into gamma hydroxybutyric acid (GHB).
As a prodrug of GHB, gamma butyrolactone is sometimes referred to as dehydrated GHB. As indicated by the term “dehydrated,” GBL does not contain as much water as GHB, and is therefore more fat-loving, or lipophilic. Compared with GHB, GBL is absorbed faster when consumed with food. This causes it to produce the desired effects faster. The duration of action of gamma butyrolactone, however, is also shorter than that of its counterpart.
he effects of gamma butyrolactone are based on its property as a prodrug of GHB. GHB is similar to the naturally produced neurotransmitter called gamma aminobutyrate (GABA). GABA is produced by the brain and acts on receptors to block nerve impulses, thereby earning the label “inhibitory” neurotransmitter. The effects of GABA include relaxation, sleep, an increased feeling of well-being, decreased anxiety and decreased muscle tone. Furthermore, GABA release is associated with increased levels of growth hormone.
Applications:
GBL is used to produce the related GHB, but is also consumed on its own. GBL can be synthesized from gamma-hydroxybutyric acid (GHB) by removal of water or by distillation from such a mixture. GHB is a naturally occurring fatty acid found throughout the human body. The inhibitory neurotransmitter gamma-aminobutyric acid (GABA) is the precursor for GHB in human brains. GHB readily crosses the blood-brain barrier with rapid onset of anxiolytic, sedative and euphoric effects. It acts in the central nervous system at the GABABB receptor and the GHB receptor.
Relaxation, calming, increased mental clarity, fat loss, use as a body or muscle "builder," recreational drug use, releasing growth hormone, improving athletic performance, trouble sleeping (insomnia), relieving depression and stress, prolonging life, improving sexual performance and pleasure, and other conditions.
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