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Product Name: Indometacin
Synonyms: AURORA KA-6542;INDOCIN;INDOmetaCIN;INDOmetaCINE;INDOMETHACIN;INDOMETHACINE;LABOTEST-BB LT00244830;1-(P-CHLOROBENZYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID
CAS: 53-86-1
MF: C19H16ClNO4
MW: 357.79
EINECS: 200-186-5
Product Categories: PHARMACEUTICALS;Active Pharmaceutical Ingredients;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Lipid signaling;INDOCIN;Other APIs
mp 155-162 °C
storage temp. Store at RT
solubility ethanol: 50 mg/mL, clear, yellow-green
Merck 4968
Stability: Stable. Incompatible with strong oxidizing agents.
Chemical Properties : White or slightly yellow crystalline powder
Usage : Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD
antiinflammatory, antipyretic, analgesic
The anti-inflammatory, antipyretic effect, mainly used for salicylates is not easy to be not significant tolerance or the efficacy of rheumatic arthritis, and ankylosing spondylitis, osteoarthritis and other light.
