[indications] of broad-spectrum antibiotics, gram negative bacteria (G-) effect is prominent, such as Escherichia coli, Pasteurella multocida, Salmonella, gas bacillus, Bacillus Proteus, grape, brucellosis and Haemophilus parainfluenzae, oral in the gut of higher concentration, mainly used in intestinal infection, on pulmonary infection, inflammatory disease of uterus, the eye, ear and skin infection and Mycoplasma induced slow shout.