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Quick Detail:
Testosterone Cypionate is the longest-estered testosterone available today. It has a half-life in the body of 15 to 16 days and is found as injectable oil. Because it reacts in the body for so long, it can cause more water retention than other steroids and is best used as bulking compound in a stack.
Testosterone Cypionate
Alias:Testosterone Cyclopentylpropionate
CAS No.:58-20-8
Molecular Formula: C27H40O3
Molecular Weight: 412.61
Purity:98%
Manufacturer:Quanao
Description:white or off-white crystalline powder.
Usage:Testosterone Cypionate is a synthetic version of the naturally produced testosterone hormone. This hormone is responsible for many different physical and mental characteristics in males. It promotes sex drive, fat loss, helps with gaining and maintaining lean muscle mass, increases bone density, and may even protect against heart disease. It is mainly used for treatment of metastatic breast cancer, and ovarian cancer, pituitary dwarfism, senile osteoporosis.
Applications:
Testosterone cypionate is a long acting ester of testosterone which is increasingly difficult to find. Before the scheduling of anabolics in the U.S., this was the most common form of testosterone available to athletes. Cyp had gained a reputation as being slightly stronger than Enanthate and became the testosterone of choice for many. Now that anabolics are controlled, this is an almost impossible find. In general, the only versions you’ll find on the black market are Sten from Mexico, which contains 75mg cyp with 25 mg propionate along with some DHEA, and Testex from Leo in Spain which contains 250mg cypionate is a light resistant ampoule. All versions of Upjohn and Steris in multi-dose vials should be looked at with extreme caution as they are very difficult to get on the black market. Counterfeits are quite easy to obtain. Real Steris products have the inking STAMPED into the box and the labels cannot be removed from the bottle. Any variation of that is definitely counterfeit. A running dosage of test cypionate is generally in the range of 200-600mg per week.
INDICATIONS AND USAGE
Testosterone cypionate Injection is indicated for replacement therapy in the male in conditions associated with symptoms of deficiency or absence of endogenous testosterone.
CONTRAINDICATIONS
1. Known hypersensitivity to the drug
2. Males with carcinoma of the breast
3. Males with known or suspected carcinoma of the prostate gland
4. Women who are or who may become pregnant
5. Patients with serious cardiac, hepatic or renal disease
WARNINGS
Hypercalcemia may occur in immobilized patients. If this occurs, the drug should be discontinued.
Prolonged use of high doses of androgens (principally the 17-α alkyl-androgens) has been associated with development of hepatic adenomas, hepatocellular carcinoma, and peliosis hepatis —all potentially life-threatening complications.
Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking.
Edema, with or without congestive heart failure, may be a serious complication in patients with pre-existing cardiac, renal or hepatic disease. Gynecomastia may develop and occasionally persists in patients being treated for hypogonadism.
This product contains benzyl alcohol. Benzyl alcohol has been reported to be associated with a fatal "Gasping Syndrome" in premature infants.
Androgen therapy should be used cautiously in healthy males with delayed puberty.
The effect on bone maturation should be monitored by assessing bone age of the wrist and hand every 6 months. In children, androgen treatment may accelerate bone maturation without producing compensatory gain in linear growth. This adverse effect may result in compromised adult stature.
This drug has not been shown to be safe and effective for the enhancement of athletic performance. Because of the potential risk of serious adverse health effects, this drug should not be used for such purpose.
PRECAUTIONS
General: Patients with benign prostatic hypertrophy may develop acute urethral obstruction.
Priapism or excessive sexual stimulation may develop. Oligospermia may occur after prolonged administration or excessive dosage. If any of these effects appear, the androgen should be stopped and if restarted, a lower dosage should be utilized.
Testosterone cypionate should not be used interchangeably with testosterone propionate because of differences in duration of action.
Testosterone cypionate is not for intravenous use.
Information for patients:
Patients should be instructed to report any of the following:
Nausea, vomiting, changes in skin color, ankle swelling, too frequent or persistent erections of the penis.
Laboratory tests:
Hemoglobin and hematocrit levels (to detect polycythemia) should be checked periodically in patients receiving long-term androgen administration.
Serum cholesterol may increase during androgen therapy.
Drug interactions:
Androgens may increase sensitivity to oral anticoagulants. Dosage of the anticoagulant may require reduction in order to maintain satisfactory therapeutic hypoprothrombinemia.
Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone.
In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, insulin requirements.
Drug/Laboratory test Interferences:
Androgens may decrease levels of thyroxinebinding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.
