17alpha-Oestradiol
Synonyms: epiestradial;
CAS: 57-91-0
EINECS: 200-023-8
Assay: 98% min.
Standard: USP34
Packing: foil bag or tin.
Delivery: Express courier.
MF: C18H24O2
MW: 272.38
Character: White Solid. Mp 176-180. solubility ethanol: 50 mg/mL, clear, colorless
Usage: Estradiol (known as a-Estradiol or 17 a-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Estradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer's disease and ischemic stroke.
Biological Activity Endogenous estrogen receptor ligand