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Erythromycin is by Streptomyces erythreus (Streptomyces erythreus) of macrolide produced (macrolide) system representation of the antibiotic. Mainly has the antibacterial activity against gram positive bacteria. LD50 is 200 to 400 mg / kg, mechanism is extended and inhibitory peptide binding and bacterial poly ribosome.
Chinese synonyms: Erythromycin; erythromycin; erythromycin A; erythromycin; erythromycin (pharmaceutical grade); Ophiopogon japonicus extract 4: 1; erythromycin, erythromycin Dimi new AI;
English Name: Erythromycin
CAS No. 114-07-8
EINECS No. 204-040-1
The molecular formula C37H67NO13
A molecular weight of 733.93
Density: the melting point of 1.2g/cm3[1]: 138-140 C
Boiling point: 818.4 degrees C at 760 mmHg
Flash point: 448.8 degrees C
Steam pressure: 4.94E-31mmHg at 25 C
3 character :white or off white crystal or powder; odorless, bitter taste; micro moisture. Soluble in methanol, ethanol or acetone, very slightly soluble in water.
4 pharmacological effects of editing the product is a macrolide antibiotic, antibacterial spectrum and penicillin approximation to gram positive bacteria, such as Staphylococcus aureus, Streptococcus pyogenes, Streptococcus, Streptococcus pneumoniae, Streptococcus faecalis, Streptococcus hemolyticus, Clostridium, diphtheria bacili, anthrax bacillus had strong inhibition. In gram negative bacteria, such as bacillus, gonococcus, spiral of Bordetella pertussis, brucellosis, Legionella, meningococcal meningitis, Haemophilus influenzae, Bacteroides, part of Bacillus dysenteriae and Escherichia coli also had certain inhibitory action. In addition, mycoplasma, actinomyces, leptospirosis, Rickettsia, chlamydia, Nocardia, few mycobacteria and Amiba protozoa has inhibitory effect. Staphylococcus aureus and Streptococcus, Staphylococcus aureus and other bacteria of the genus of the product easy to resistance.
Characteristic is the resistance of the strains to penicillin, in the drug sensitive. The mechanism of action is mainly 50S subunit ribosome combined inhibitory peptide acyltransferase, affect the shift process of ribosomes, hinder peptide growth, inhibiting bacterial protein synthesis, fasten bacteriostatic agent
ShangHai YiJing Industrial Co,LTD. is a comprehensive and high-tech enterprise special in chemical synthetic drug, pharmaceutical intermediates,
Chemical raw materials, chemical antisepsis, flavor & essence, and food additive, integrating R&D, manufacturing, operating and marketing into an
organic whole. The company is located in Xiaogan city, nearby national highways of No.107, marched with ShangHai city.
Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large-sized, medium-sized workshops
and QA and research center with advanced equipments.
At present, our main products are cinnamate series, anabolics series, L-carnitine,Melatonin, collagen and so on. Our products reach the advanced
standard of domestic market, many of which reach the international standard, pass Kocher certificate and ISO9001.
Our Staff will pursue high quality and perfect brand with untiring efforts, and inherit company spirit on " energy-saving, factual, enterprising,
innovative ", follow the company management theory of "lives, services or soul of quality ",with the first-class products and high-quality
service to meet market's demands.
