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Name:Cinacalcet hydrochloride
Synonyms:Mimpara;Regpara;Sensipar;1-Naphthalenemethanamine,a-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-,hydrochloride, (aR)-(9CI);N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride; Cinacalcet HCl;Cinacalcet Hydrochloride; KRN 1493;Mimpara;
CAS Number:364782-34-3
MW: C22H22F3N.HCl
MF :393.88
Mol File: 694495-47-1.mol
Boiling Point:440.9℃at760mmHg
Melting point:177-182℃
Flash Point:220.5℃
Loss on drying:≤0.5%
Water:≤0.5%
Heavy metals:≤20ppm
Storage:-20°C Freezer
Related substances:Any single impurity ≤0.1% Total impurity≤1.0%
Solubility:Soluble in water and ethanol;sparingly soluble in ethyl acetate
Appearance:White crystalline powder
Usage: is used to treat secondary hyperparathyroidism. Cinacalcet is also indicated for the treatment of hypercalcemia in patients with parathyroid carcinoma.Cinacalcet is also indicated for the treatment of hypercalcemia in patients with parathyroid carcinoma.
Cinacalcet hcl Function:
(1)Used in the treatment of dialysis patients with chronic kidney disease (CKD) of secondary parathyroid function already;
(2) For the treatment of hypercalcemia of parathyroid carcinoma;
(3)Severe patients with hypercalcemia HPT Lord who cannot accept parathyroidectomy.
Indications and Usage:
Treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis; hypercalcemia in patients with parathyroid carcinoma; for the treatment of severe hypercalcemia in patients with primary hyperparathyroidism who are unable to undergo parathyroidectomy.
