betamethasone 17-valerate

Synonyms: betamethasone pentanoate; Betamethasone Valerate; 1,4-Pregnadiene-11b,17a,21-triol-9a-fluoro-16b-methyl-3,20-dione 17-valerate; 9-Fluoro-11beta,17,21-trihydroxy-16bet; methylpregna-1,4-diene-3,20-dione 17-valerate

CAS: 2152-44-5

EINECS: 218-439-3

MF: C27H37FO6

MW: 476.5775

Assay: 99%

Appearance: White powder

Density 1.24g/cm3

Boiling point 598.9°C at 760 mmHg

Refractive index 1.56

Flash point 316°C

Vapour Pressur 7.72E-17mmHg at 25°C

2.  Descriptions:

Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone does not cause water retention. It is applied as a topical cream, ointment, foam, lotion or gel to treat itching. Betamethasone sodium phosphate is sometimes prescribed as an intramuscular injection (I.M) for itching from various ailments, including allergic reactions to poison ivy and similar plants.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system

Betamethasone is a corticosteroid used as a topical cream to relieve skin irritation, such as itching and flaking from eczema. It is used as a treatment for local psoriasis, as betamethasone dipropionate and salicylic acid, or as the combination betamethasone/calcipotriol. Betamethasone sodium phosphate is used orally and via injection with the same indications as other steroids.

In a randomized controlled trial Betamethasone was shown to reduce some of the ataxia symptoms associated with Ataxia Telangiectasia (A-T) by 28-31%.

Alternative medical approach for large microcystic CCAMs - Betamethasone therapy

Betamethasone is also used prior to delivery of a preterm baby to help prepare the lung for breathing.