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1. Product Name: Gonadorelin
Synonyms: LUTEINIZING HORMONE-RELEASING HORMONE (SEA BREAM);LUTENIZING HORMONE RELEASING HORMONE HUMAN;LUTEINIZING HORMONE-RELEASING HORMONE (LAMPREY III);LUTEINIZING HORMONE-RELEASING HORMONE (LH-RH), HUMAN;LUTEINIZING HORMONE RELEASING HORMONE HUMAN;LUTEINIZING HORMONE RELEASING HORMONE (HUMAN) PORCINE, RAT;LUTEINIZING HORMONE-RELEASING FACTOR (LAMPREY III);LUTEINIZING HORMONE-RELEASING HORMONEACETATE
CAS: 33515-09-2
MF: C55H75N17O13
MW: 1182.29
EINECS: 232-895-08
Purity (HPLC): ≥98.0%
Function: Gonadorelin is a medicine that is the same as gonadotropin-releasing hormone (GnRH) that is naturally released from the hypothalamus gland.
Storage: a cool(2~8 °C) & dry place
Appearance:White or slightly yellowish powder White powder
SolubilitySoluble in water or 1% acetic acid at a concentration of 1mg/ml to give a clear, colorless solutionConforms
Identity by HPLCThe retention is same with the reference substanceConforms
Specific Optical Rotation-65.0- -75.0° (c=0.5, 95%HAc)-71.3°
Amino Acid Composition± 10% of theoreticalConforms
Peptide Purity (By HPLC)≥ 98.0% by area integration98.8%
Related Substance (By HPLC)Total Impurities(%) ≤ 2.0% Largest Single Impurity (%) ≤ 1.0%1.2% 0.7%
Acetate Content≤ 15.0%13.8%
Water Content (Karl Fischer)≤ 5.0%1.5%
Gonadorelin Desctiprion:
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary.
GnRH is available as gonadorelin hydrochloride )and gonadorelin diacetate tetrahydrate for injectable use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.
Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.
Gonadorelin Application:
Gonadorelin is a medicine that is the same as gonadotropin-releasing hormone (GnRH) that is naturally released from the hypothalamus gland.
GnRH causes the pituitary gland to release other hormones (luteinizing hormone [LH] and follicle-stimulating hormone [FSH]). LH and FSH control development in children and fertility in adults.
Gonadorelin is used to test how well the hypothalamus and the pituitary glands are working. It is also used to cause ovulation (release of an egg from the ovary) in women who do not have regular ovulation and menstrual periods because the hypothalamus gland does not release enough GnRH.
Additional Info.
Export Markets:Global
Origin:China
Certification:SGS
Brand Name:Mengfeis
Packing:according to the customer request
Payment:Western unio,Money gram,T/T,Bitcoin
Shipment:HKEMS,EMS,FedEx,TNT,DHL,UPS,Aramex
Delivery:5-7 Working Days Door to Door
Production Capacity:3600kg/Month
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