Human PCDHGA3 ELISA kit

Product Name:

Human Protocadherin gamma-A3(PCDHGA3) ELISA kit

Product Type : ELISA Kit

Code : CSB-EL017583HU

Size : 96T,5×96T,10×96T

Uniprot NO. : Q9Y5H0

Abbreviation : PCDHGA3

Protein Biological Process 1 : Cell Adhesion

Alias : PCDH-GAMMA-A3,

Species : Human

Protein Biological Process 3 : Cell adhesion

Sample Types : serum, plasma, tissue homogenates

Detect Range : 62.5 pg/ml-4000 pg/ml

Research Area : Neuroscience

Target details : This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.