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Yohimbine is a mild MAOI with stimulant and aphrodisiac effects. It is sold as prescription medicine in pure form for the treatment of sexual dysfunction. Yohimbine was explored as a remedy for type 2 diabetes in animal and human models carrying polymorphisms of the α2A-adrenergic receptor gene.
Common brand names for Yohimbine are: Erex, Testomar, Yocon, Yohimar, Yohimbe.
Description:
Yohimbine Hydrochloride
Alias: Corynine;Aphrodine
CAS No: 65-19-0
Einecs No: 200-600-4
MF: C21H27ClN2O3
MW: 390.91
Purity: 98%
Appearance:White crystalline powder, taste slightly bitter.Soluble in chloroform, soluble in methanol, ethanol, slightly soluble in water.
Applications:
Increase muscular tension or urinary function no damage sex; Accelerate human body energy metabolism, increase energy supply.
Yohimbine has been shown in human studies to be effective in the treatment of male impotence. Yohimbine has been shown to be effective in the treatment of orgasmic dysfunction in men. Yohimbine has also been used to treat hypoactive sexual desire disorder (reduced libido) in women.
Yohimbine has been used to facilitate recall of traumatic memories in the treatment of post traumatic stress disorder (PTSD). Use of yohimbine outside therapeutic settings may not be appropriate for persons suffering from PTSD. In pharmacology, yohimbine is used as a probe for α2-adrenoceptor. In veterinary medicine, yohimbine is used to reverse anesthesia from the drug xylazine in small and large animals.
Specifications:
ANALYSIS |
SPECIFICATION |
RESULTS |
Appearance |
White fine powder |
Complies |
Odor |
Characteristic |
Complies |
Assay (HPLC) On dry basis |
Yohimbine HCL≥98.0% |
99. 3% |
Sieve analysis |
NLT 100% pass 80 mesh |
Complies |
Melting point |
285-290°C |
288.2ºC |
Boiling point |
542.979°C at 760 mmHg |
Complies |
Flash point |
282.184°C |
Complies |
Vapour Pressur |
0mmHg at 25°C |
Complies |
Specific Rotation |
+100º to +105º |
+103.80º |
Solubility |
Slightly soluble in Water/Alcohol |
Complies |
Loss on Drying |
≤1% |
0.7% |
Residue on Ignition |
≤1% |
0.87% |
Heavy metal |
<15ppm |
<10ppm |
As |
<2.0ppm |
<1ppm |
Pb |
<1.0ppm |
<0.4ppm |
Cd |
<1.0ppm |
0ppm |
Hg |
<0.1ppm |
0ppm |
Residual Solvents |
Eur.Pharm. |
Complies |
Microbiology |
||
Total Plate Count |
<1000cfu/g |
Complies |
Yeast & Moulds |
<100cfu/g |
Complies |
E.Coli |
Negative |
Complies |
Salmonella |
Negative |
Complies |
S.aureus |
Negative |
Complies |
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